If you've been treated for depression but your symptoms haven't improved, you may have treatment-resistant depression. Taking an antidepressant or going to psychological counseling (psychotherapy) eases depression symptoms for most people. But with treatment-resistant depression, standard treatments aren't enough. They may not help much at all, or your symptoms may improve only to keep coming back. Treatment-resistant depression symptoms can range from mild to severe and may require trying a number of approaches to identify what helps.
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